Main Article Content
Abstract
Fisetin (3, 3, 4, 7-tetrahydroxyflavone) is a flavonoid found in various vegetables, fruits, nuts, teas and derived products. Fisetin possesses excellent neuroprotective, antioxidant, anti-inflammatory, anticancer, hepatoprotective and anti-diabetic effect through various molecular mechanisms. Fisetin has limitations in clinical application because of its physicochemical properties i.e. low water solubility, low physical and chemical stability that possesses dissolution rate-limited oral bioavailability.