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Abstract
Helicobacter pylori, residing in human gut, has been associated with several threatening diseases that include gastric and duodenal ulcers and gastric adenocarcinoma. Helicobacter pylori is an intimidating pathogen that resides in human gastrointestinal tract and causes gastritis, peptic ulcers and gastric adenocarcinoma on acquiring pathogenic phenotype. Present research endeavor has been targeted to deciphering the attributes of codon usage in Helicobacter pylori 35A. Factors like genomic compositional constraint, selection pressure for translational exactitude and gene length were imperative indices in influencing the mode of codon usage. AT compositional constraint was noted to be the most decisive factor. Present research approach confers information that might be beneficial for biological domains associated with pathogenomics of Helicobacter pylori and devise mutational experiments to combat associated infection.